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For more than 20 years, Laclede has led in the development of biological products, which utilize the body’s natural defense systems for the prevention and treatment of gum disease due to dry mouth. The company s products are sold under the brand name of Biot ne. The strength of the Biot ne products lies in their ingredients; they contain antibacterial enzymes found naturally in human saliva. Biot ne contains three primary enzymes glucose oxidase, lactoperoxidase and lysozyme, which are balanced to function in boosting and replenishing saliva’s own defenses. Laclede s range of products includes Biot ne dry mouth toothpaste, Biot ne dry mouth gum, Biot ne gentle mouthwash, Oral Balance moisturizing gel and Oral Balance dry mouth liquid. Registered Dental Hygienists, the Oral Cancer Foundation and Dental Economics have endorsed the company s products. Laclede is headquartered in Rancho Dominguez, Calif.